Purgy 

Anti-spam software for Windows. It accepts emails from senders you trust while asking unknown senders to verify themselves by replying to an email. After positive verification it adds them to your approved sender list and delivers all their messages.
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1Click Spam Shield 

1 Click Spam Shield is the solution for eliminating one of the biggest threats of the mailing systems, spam. Receive all your email safely and securely, all filtering being done, resulting in a clean Inbox with just solicited mail and no more junk.
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Spam Bully 3 for Outlook 

Outlook Bayesian spam filter. Allow/Block list. Bounce spam back to spammers. Report spammers. Forward only good email to your cellphone. Auto delete spam. Challenge emails. Stats. Convert the toolbar into your own language. Customizable.
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VisNetic MailServer 

VisNetic Mail Server is a high performance mail server with an extensive, highly configurable feature set. This secure mail server is also ideal for use as a gateway mail server, features built-in anti spam, Web mail and an instant messaging server.
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GFI MailEssentials for Exchange/SMTP 

Spam protection and email management at server level. GFI MailEssentials offers a fast set-up and a high spam detection rate using Bayesian analysis and other methods - no configuration required. Also adds key email tools to your mail server.
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Spam Bully 3 for Outlook Express 

Outlook Express Bayesian spam filter. Allow/Block list. Bounce spam back to spammers. Report spammers. Forward only good email to your cellphone. Auto delete spam. Challenge emails. Stats. Convert the toolbar into your own language. Customizable.
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