PlexMailer 

PlexMailer is an anti-spam software. It supports POP3, IMAP, LDAP, NNTP and MBOX protocols. It comes with dozens of filters such as Bayesian and realtime blacklists. Also, it supports server side options and integration with other products.
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~ 1 SpamItBack 

Get spammers back, and send your own message telling them to stop spamming once, a thousand times, or as many times as you want back to them. And get a hi-score at the same time.
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EClean 

EClean, a pre-mail service hides your mailto: links and authenticates and quarantines your legitimate E-mail. Letting you delete UCEs even before they get in your inbox. This clever solution created for Webmasters, works for anyone with a POP Mailbox
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Ad Nuker Popup Blocker & Spam Filter 

Filter Junk E-Mail Spam, Ads, Pop Ups advertising, Viruses, Tojans & Spyware. Works with POP3 & IMAP. This FREE tool uses intelligent filtering of annoying Popup ads, e-mail spam, Spyware, Adware, Trojans, Viruses, Spyware Cookies and much much more
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xTerminator 

Block spam and most of worms before they even reach your mailbox. You'll be able to delete unwanted messages directly from the server thus saving valuable time and bandwidth.
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Ella for Spam FREE 

Ella for Spam FREE is the FREE version of the award winning Ella for Spam Control for Outlook 2000/02/03 (sorry no Outlook Express) Ella is THE Smart Inbox Assistant, learning by example to quickly organize and automate the processing of email.
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